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Literature summary for 2.7.11.17 extracted from
- Identification of the isoforms of Ca2+/calmodulin-dependent protein kinase II and expression of brain-derived neurotrophic factor mRNAs in the substantia nigra (2006), J. Neurochem., 96, 195-203.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytoplasm | CaMKII isozyme delta1-4 in dopaminergic neurons of substantia nigra | Rattus norvegicus | 5737 | - |
| additional information | subcellular distribution of isozymes and splicing variants in substantia nigra | Rattus norvegicus | - |
- |
| nucleus | CaMKII isozyme delta1-4 in dopaminergic neurons of substantia nigra | Rattus norvegicus | 5634 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Rattus norvegicus | isozyme CaMKIIdelta3 is involved in the expression of brain-derive neurotrophic factor, BDNF, in the substantia nigra | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
CaMKII isozymes alpha, beta, gamma, and delta, each with a number of splicing variants | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Rattus norvegicus | - |
| central nervous system | - |
Rattus norvegicus | - |
| additional information | tissue distribution of isozymes in the central nervous system | Rattus norvegicus | - |
| neuron | predominant expression of CaMKII isozymes gammaA, gammaC, delta1, and delta3 in dopaminergic neurons of substantia nigra | Rattus norvegicus | - |
| substantia nigra | predominant expression of CaMKII isozymes gammaA, gammaC, delta1, and delta3 in dopaminergic neurons | Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | isozyme CaMKIIdelta3 is involved in the expression of brain-derive neurotrophic factor, BDNF, in the substantia nigra | Rattus norvegicus | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Ca2+/calmodulin-dependent protein kinase II | - |
Rattus norvegicus |
| CaMKIIalpha | - |
Rattus norvegicus |
| CaMKIIbeta | - |
Rattus norvegicus |
| CaMKIIdelta | - |
Rattus norvegicus |
| CaMKIIgamma | - |
Rattus norvegicus |
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Release 2023.1 (January 2023)
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